{"quotes":[{"text":"Our analyses of the FDA data showed relatively little difference between the effects of antidepressants and the effects of placebos. Indeed, the effects were so small that they did not qualify as clinically significant. The drug companies knew how small the effect of their medications were compared to placebos, and so did the FDA and other regulatory agencies. The companies found various ways to make the data seem more favorable to their products, and the FDA helped them keep their negative data secret. In fact, in some instances, the FDA urged the companies to keep negative data hidden, even when the companies wanted to reveal them. My colleagues and I hadn't really discovered anything new. We had merely revealed their 'dirty little secret'.","author":"Irving Kirsch","tags":["antidepressants","bad","drug-companies","fda","ineffective","secret"],"id":10289,"author_id":"Irving+Kirsch"},{"text":"Unbeknownst to me, from the beginning of freshman year Rob and Oswaldo had been drawn away from Yale via their friends on the dining hall and custodial staffs, outward into the city of New Haven. Rob considered these excursions a much-needed dose of reality, the social equivalent of an antidepressant.","author":"Jeff Hobbs","tags":["antidepressants","college"],"id":16582,"author_id":"Jeff+Hobbs"},{"text":"The irony of taking Anti Depressants: you take them to feel good but they also make you feel bad or worse because you worry about your purse.","author":"Mico Monsalve","tags":["antidepressants","depression","psychiatry","psychosis","therapy"],"id":68202,"author_id":"Mico+Monsalve"},{"text":"Medications used to treat psychiatric disorders are commonly referred to as psychotropic drugs. These drugs are commonly described by their major clinical application, for example, antidepressants, antipsychotics, mood stabilizers, anxiolytics, hypnotics, cognitive enhancers, and stimulants. A problem with this approach is that these drugs have multiple indicators. For example, selective serotonin reuptake inhibitors (SSRls) are both antidepressants and anxiolytics, and the serotonin-dopamine antagonists (SDAs) are both anxiolytics and mood stabilizers.","author":"Benjamin James Sadock","tags":["anti-depressant","antidepressants","anxiety","anxiolytic","depression-treatment","dopamine","drugs","medication","meds","mood-stabilizers","psychiatric-disorders","psychiatric-drugs","psychiatry","psychosis","psychotropic","serotonin","stimulants"],"id":110602,"author_id":"Benjamin+James+Sadock"},{"text":"I'm generally a happy person -with the help of antidepressants, that is- so there is something to be said for surrounding myself with happy people.","author":"Rachel Machacek","tags":["antidepressants","happiness","happy"],"id":162999,"author_id":"Rachel+Machacek"},{"text":"Psychotropic drugs have also been organized according to structure (e.G., tricyclic), mechanism (e.G., monoamine, oxidase inhibitor [MAOI]), history (first generation, traditional), uniqueness (e.G., atypical), or indication (e.G., antidepressant). A further problem is that many drugs used to treat medical and neurological conditions are routinely used to treat psychiatric disorders.","author":"Benjamin James Sadock","tags":["anti-depressant","anti-depressants","antidepressants","anxiety","depressant","depression","drugs","medication","mental-health-stigma","mental-illness-stigma","neurological","psychiatric-drugs","psychiatric-treatment","psychiatry","psychosis","psychotropic"],"id":169602,"author_id":"Benjamin+James+Sadock"},{"text":"For people who are depressed, and especially for those who do not receive enough benefit from medication of for whom the side effects of antidepressants are troubling, the fact that placebos can duplicate much of the effects of antidepressants should be taken as good news. It means that there are other ways of alleviating depression. As we have seen, treatments like psychotherapy and physical exercise are at least as effective as antidepressant drugs and more effective than placebos. In particular, CBT has been shown to lower the risk of relapsing into depression for years after treatment has ended, making it particularly cost effective.","author":"Irving Kirsch","tags":["antidepressants","cognitive-behavior-therapy","depression","good-news","placebo","psychotherapy"],"id":211910,"author_id":"Irving+Kirsch"},{"text":"My sadness is beautiful. It infuses everything I do. It is at the core of my identity and always has been, just as happiness is in some people. I refuse to be told that it's a flaw. I will not mute it with medications for the sake of society. I will hold it close to me and celebrate it rightfully while the rest of the world fails to see it for what it is and it will be their loss.","author":"Ashly Lorenzana","tags":["antidepressants","depression","human","identity","medicine","melancholy","mental-health","mental-illness","mood-disorders","moody","personality","psychiatry","psychology","sadness"],"id":223014,"author_id":"Ashly+Lorenzana"},{"text":"Even if we accept the view that biochemical imbalances may contribute to depression and suicide, it is a mistake to assume that the biochemical aspect of the problem is entirely within the victim. It is also partly within the physiological makeup of the people around the suicide.","author":"David L. Conroy","tags":["antidepressants","biochemical-imbalance","depression","medication","physiological-chemistry","society","suicide"],"id":241235,"author_id":"David+L.+Conroy"},{"text":"How many artists have created while drunk, high on laudanum, opium, chloral or amphetamines? What have antidepressants ever done for culture?","author":"Hanif Kureishi","tags":["antidepressants","artists"],"id":269562,"author_id":"Hanif+Kureishi"}],"pagination":{"page":1,"page_size":10,"total":14,"pages":2,"next":"?page=2\u0026page_size=10"}}